Oxytocin Receptor Pathways
Oxytocin is studied for receptor-mediated signaling in neuroendocrine and peripheral tissue models.
Overview
What is Oxytocin Acetate?
Oxytocin Acetate is a nonapeptide research compound studied for oxytocin receptor signaling, neuroendocrine biology, social-behavior models, and smooth-muscle receptor pharmacology. Laboratory research examines G protein-coupled receptor activation, calcium signaling, and central nervous system pathways.
Oxytocin Acetate (Oxytocin Acetate Salt) is supplied strictly as a reference material for in vitro and preclinical investigation. All characterization data described here is drawn from peer-reviewed literature and laboratory analysis; nothing herein constitutes a claim of clinical effect in humans.
Investigational Scope
Documented Research Areas
The following domains summarize directions explored across published studies and laboratory models. Each reflects observations reported in rodent models, in vitro systems, or the peer-reviewed record.
Calcium Signaling Assays
Research examines Gq-coupled oxytocin receptor activation and intracellular calcium mobilization.
Social Behavior Models
Animal-model studies investigate central oxytocin pathways in social recognition, stress, and affiliative behavior research.
Contractility Models
Peripheral receptor studies evaluate smooth-muscle contractility and downstream signaling under controlled assay conditions.
Proposed Mechanism
Mechanistic Pathway
Mechanistic steps below are hypothesized from in vitro assays and animal-model data reported in the literature. They describe biochemical interactions observed under controlled experimental conditions.
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1
Oxytocin Receptor Agonism
Oxytocin binds the oxytocin receptor, a G protein-coupled receptor expressed in central and peripheral tissues.
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2
Phospholipase C Activation
Receptor activation can trigger PLC signaling, IP3 generation, and calcium release in responsive cells.
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3
Central Neuromodulation
Research models examine oxytocinergic signaling in hypothalamic and limbic circuits associated with neuroendocrine regulation.
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4
Disulfide-Constrained Structure
The intramolecular disulfide bridge stabilizes the cyclic nonapeptide structure important for receptor recognition.
Technical Data
Molecular Specifications
| Amino Acid Sequence | Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (disulfide bridge Cys1-Cys6) |
|---|---|
| Molecular Weight | 1,007.2 g/mol |
| Molecular Formula | C43H66N12O12S2 |
| CAS Number | 50-56-6 |
| Storage | -20°C long-term, protected from light and moisture |
References
Selected Literature
The following peer-reviewed references informed the research summaries on this page. Citations are provided for scientific context only.
- Gimpl G & Fahrenholz F. (2001). The oxytocin receptor system: structure, function, and regulation. Physiological Reviews, 81(2), 629-683.
- Jurek B & Neumann ID. (2018). The oxytocin receptor: from intracellular signaling to behavior. Physiological Reviews, 98(3), 1805-1908.
- Donaldson ZR & Young LJ. (2008). Oxytocin, vasopressin, and the neurogenetics of sociality. Science, 322(5903), 900-904.
- Manning M, et al. (2012). Oxytocin and vasopressin agonists and antagonists as research tools and therapeutic agents. Journal of Neuroendocrinology, 24(4), 609-628.
- Busnelli M & Chini B. (2018). Molecular basis of oxytocin receptor signalling in the brain. Frontiers in Endocrinology, 9, 1-12.
Research Disclaimer
This product is intended strictly for laboratory research purposes only. It is not a drug, food, cosmetic, or dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease. It is not for human or animal consumption. All information presented is derived from published scientific literature and is provided for educational reference only. By purchasing, the buyer affirms they are a qualified researcher or institution and assume full responsibility for the safe and lawful handling of this material.